It is already confirmed that The Crown will see Imelda Staunton replacing Olivia Colman as Queen Elizabeth II for the fifth and sixth season. This continues the series' process of recasting every two seasons so as to naturally age up the biographical characters that the series depicts. In addition, Leslie Manville will play Princess Margaret and Jonathan Pryce will play Prince Philip. And now, it's been confirmed that Dominic West is in talks to take over for Prince Charles.
The irony comes in that, in the expected time periods the last two seasons of the show will depict, Prince Charles was revealed to be having an affair with Camilla Parker Bowles whilst married to Princess Diana. Parker Bowles would go on to become Charles’ second wife. In addition, prior to this announcement, West's most well-known project was the series The Affair. So, in the case of West anyway, art is imitating life AND art. Stay tuned!